2010 | Press Release
The First Visualization of Deformation Behavior of Endothelial Cells in the Simulated Blood Stream - Elucidation of Cellular Response Mechanism to Mechanical Stimulation -
A research group led by Professor Masaaki Sato at Graduate School of Biomedical Engineering, Tohoku University, Assistant Professor Naoya Sakamoto at Graduate School of Engineering, Tohoku University and Yosuke Ueki, Doctoral student at Tohoku University and Fellow at Japan Science and Technology Agency (JST), has successfully visualized cross-section images of endothelial cells (ECs) in real time. The group has first observed deformation behavior of ECs in the simulated blood stream.
The achievement will help to clarify a cellular response mechanism to mechanical stimulation to explain vessel pathophysiology, and contribute to the development of regenerative medicine.
The research results have been published online in Biochemical and Biophysical Research Communications.
Professor Masaaki Sato
Graduate School of Biomedical Engineering, Tohoku University
Assistant Professor Naoya Sakamoto
Graduate School of Engineering, Tohoku University