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Identification of the Biomarkers for Progression in Diabetes Complications

-Blood methylglyoxal levelpredicts the progression of diabetic vascular disorders after 5 years-

 Recently, a rapid increase in the number of diabetic patients and related vascular disorders such as myocardial and brain infarctions have been a critical issue. It has been expected to establish a detection method of highly possible vascular disorders in diabetic patients so that intensive interventions are available. In this study, a research group led by Associate Professor Susumu Ogawa at Health Administration Center, Tohoku University and group by division of Nephology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine clarified that vascular disorders in diabetes cases with high methylglyoxal level have further progressed over 5 years. Testing blood methylglyoxal level is expected to help selecting patients to receive intensive intervention and to provide effective prevention of vascular disorders.  The results of the present research have been published online in Hypertension on July 19, 2010. The title of the paper is “Methylglyoxal Is a Predictor in Type 2 Diabetic Patients of Intima-Media Thickening and Elevation of Blood Pressure.”

More Information (Japanese)PDF

[Contact]
Associate Professor Susumu Ogawa
Graduate School of Medicine,
Center for the Advancement of Higher Education,
Health Administration Center, Tohoku University
TEL: +81-22-717-7166
E-mail: ogawa-s*mail.tains.tohoku.ac.jp (Replace * with @)

(Public Relations)
Associate Professor Fuji Nagami
Public Relations Office at Tohoku University Graduate School of Medicine
TEL: +81-22-717-7891
FAX: +81-22-717-8187
E-mail: f-nagami*med.tohoku.ac.jp (Replace * with @)
 

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