Tohoku University has successfully induced ameloblasts, which form enamel on teeth, from induced pluripotent stem cells (iPS cells), in the process of the elucidation of stem-cell fate determination via interactions with dental epithelium. This achievement has been acquired in collaboration with Dr. Makiko Arakaki at Tohoku University Hospital, Professor Satoshi Fukumoto at Graduate School of Dentistry, Tohoku University, National Institutes of Health, Iwate Medical University and Tokyo University of Science.

 The research result has been published online in The Journal of Biological Chemistry. The paper's title is "Role of epithelial-stem cell interactions during dental cell differentiation".

More information (Japanese)

[Contact]

Professor Satoshi Fukumoto

Division of Pediatric Dentistry

Graduate School of Dentistry, Tohoku University

Tel: +81-22-717-8380

Administration Division of Graduate School of Dentistry, Tohoku University

Tel: +81-22-717-8244