A sensor system called "Bio-LSI" has been developed for label-free and real-time imaging of biomolecules. 20 × 20 amperometric electrodes integrated in a LSI act as a pixel sensor array to provide images indicating a transient of biomolecules through a change in current response.

 Bio-LSI has a potential for wide applications in the medical and bioscience fields, including an observation for neurotransmitter related to brain diseases and an evaluation for implantable tissues in regenerative medicine. Bio-LSI also provides an array-type platform for simultaneous and comprehensive analysis of DNA, proteins, and etc.

 This promising system was brought by a fusion research of world-leading MEMS and LSI technologies supported by Japan Science and Technology Agency (JST). This research, published in a journal, Lab on a Chip, by Royal Society of Chemistry (United Kingdom) on the electronic version on June 13, was conducted by a research group of Tohoku University Micro Systems Integration Center and WPI Advanced Institute for Materials Research (Professor Tomokazu Matsue, Professor Masayoshi Esashi, Dr. Kumi Y. Inoue), Japan Aviation Electronics Industry, Ltd. and Toppan Technical Design Center CO, Ltd.

More information (Japanese)

[Contact]

Professor Tomokazu Matsue

WPI Advanced Institute for Materials Research, Tohoku University

TEL: +81-22-795-7209

E-mail: matsue*bioinfo.che.tohoku.ac.jp (Replace * with @)

Dr. Kumi Inoue

Tohoku University Micro Systems Integration Center

TEL: +81-22-795-7281

E-mail: inoue*bioinfo.che.tohoku.ac.jp (Replace * with @)