Research groups led by Professor Masayuki Yamamoto at Tohoku University Graduate School of Medicine and by Vice-Councilor Researcher Masaaki Komatsu at Tokyo Metropolitan Institute of Medical Science have jointly discovered that Keap1, which acts as a sensor for reactive oxygen species and toxic substances, is degraded by the autophagy mechanism. This discovery is important for understanding of molecular mechanisms of the stress response in living organisms and is going to be published in Proceedings of the National Academy of Sciences of the United States of America (PNAS).

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[Contact]

(About the research)

Assistant Professor Keiko Taguchi

Medical Biochemistry, Tohoku University Graduate School of Medicine

TEL: +81-22-717-8085

E-mail: keiko*med.tohoku.ac.jp (Replace * with @)

(Public Relations)

Associate Professor Fuji Nagami

Public Relations Office of Tohoku University Graduate School of Medicine

Tel: +81-22-717-7908

Fax: +81-22-717-8187

E-mail: f-nagami*med.tohoku.ac.jp (Replace * with @)