The research group led by Professor Toru Nakazawa of Tohoku University Graduate School of Medicine (1) found that oxidative stress and activation of calpain molecules are included in the mechanism of retinal ganglion cells death caused by diabetic retinopathy and metabolic stress, and (2) succeeded in delaying retinal ganglion cell death by therapeutic use of the calpain inhibitor. The research results will be published in the international scientific journal Neurobiology of Disease. The paper's title is "Metabolic stress response implicated in diabetic retinopathy: The role of calpain, and the therapeutic impact of calpain inhibitor."

More information (Japanese)

[Contact]

(About the research)

Professor Toru Nakazawa

Laboratory of Ophthalmology

Tohoku University Graduate School of Medicine

TEL: +81-22-717-7294

E-mail: ntoru*oph.med.tohoku.ac.jp (Replace * with @)

Assistant Professor Yuji Tanaka

Laboratory of Ophthalmology

Tohoku University Graduate School of Medicine

TEL: +81-22-717-7294

E-mail: ytanaka*oph.med.tohoku.ac.jp (Replace * with @)

(Public Relations)

Associate Professor Fuji Nagami

Public Relations Office of Tohoku University Graduate School of Medicine

TEL: +81-22-717-7908 FAX: +81-22-717-8187

E-mail: f-nagami*med.tohoku.ac.jp (Replace * with @)